Fig. 4.
The values of loss of righting reflex ED50 for mice to four xenon isotopes alone. The data of loss of righting reflex were calculated by the fractions of loss of righting reflex ED50 of xenon isotopes attributable to constant 0.50% isoflurane with isoflurane ED50 as 0.64%. The values of loss of righting reflex ED50 of xenon 132 (132Xe) and xenon 134 (134Xe) are identical. Loss of righting reflex ED50 of xenon 129 (129Xe) is significantly higher than 132Xe and 134Xe. Loss of righting reflex ED50 of xenon 131 (131Xe) is significantly higher than 132Xe and 134Xe but significantly lower than 129Xe. Data are shown as mean (SD), n = 20 mice per group. **P < 0.001; ****P < 0.0001; N.S. = not significantly different (one-way ANOVA followed by the Bonferroni correction as a post hoc test).