Fig. 1.
Schematic showing the protocol sequence for the main interventional part of the study. The gray boxes labeled Q represent the time periods during which seizure-like event frequency was quantified for statistical comparison. Note that the maximum ketamine effect tended to occur in the period immediately after terminating drug perfusion, hence the alignment of Q3 with the beginning of the Wash period. BaCl2 = barium chloride; CsCl = cesium chloride; Low K = low potassium (1.5 mM); Wash = perfusion with drug-free artificial cerebrospinal fluid.