Figure 2. Myocardial infarct size (IF) expressed as a percentage of the area at risk (AAR). CON = control; PC = ischemic preconditioning; I = administration of isoflurane until 5 min before prolonged LAD occlusion; I + PC = administration of isoflurane before and during ischemic preconditioning; I + M = discontinuation of isoflurane 30 min (memory period) before prolonged LAD occlusion; I + M + GLB = pretreatment with glyburide followed by discontinuation of isoflurane 30 min before prolonged LAD occlusion; GLB = pretreatment with glyburide. *Significantly (P < 0.05) different from CON. (dagger)Significantly (P <0.05) different from GLB. (section sign)1 + M + GLB significantly (P <0.05) different from I + M.