Figure 5. Competition of the enantiomers for one binding site. Apparent IC⁵⁰values of S(+) ketamine for the flicker K⁺concentrations of R(-) ketamine. Dashed line shows theoretical change of apparent IC⁵⁰values of S(+) ketamine assuming models of either competition of both enantiomers for one binding site or of two independent binding sites. The dotted lines show 95% confidence interval for the data (number of outside-out patches is indicated next to each data point).