Figure 3. Whole-cell calcium current traces obtained in response to voltage steps to -20 mV to activate low-voltage-activated (LVA) calcium current (A) and +20 mV to activate high-voltage-activated (HVA) calcium current (B). Traces were obtained before (control), during (enflurane), and after (recovery) exposure of the cell to 2 mM enflurane. Enflurane reduced the peak magnitude of both LVA (A) and HVA (B) calcium currents, but the reduction in LVA current was much greater.