Fig. 6.
Anesthetic effects on β3H267C sulfhydryl modification rates. Each column represents group mean ± SEM calculated from individual oocyte modification rate results. Modification conditions are labeled: 10 nM p-chloromercuribenzensulfonate (pCMBS); 1 mM γ-aminobutyric acid (GABA); 10 μM propofol (PRO); 10 μM etomidate (ETO); 10 μM alphaxalone (ALF); 8 μM R-5-allyl-1-methyl-5-(m-trifluoromethyl- diazirinylphenyl) barbituric acid (mTFD-MPAB). Results with anesthetics were compared with pCMBS plus GABA (Kruskal–Wallis with Dunn multiple comparisons), indicating that only MPAB significantly slowed modification. *P = 0.011; n.s. = no significant difference from control (+GABA).