Time-weighted average (TWA) mean arterial pressure (MAP) under absolute and relative thresholds for myocardial injury after noncardiac surgery (MINS). Univariable and multivariable relationship between MINS and TWA MAP under absolute and relative thresholds. (A) and (C) Estimated probability of MINS were from the univariable moving-window with the width of 10% data; (B) and (D) were from multivariable logistic regression smoothed by restricted cubic spline with three degrees and knots at 10th, 50th, and 90th percentiles of given exposure variable. Multivariable models adjusted for covariates in table 1. (A) and (B) show that MAP less than 65 mmHg was a change point since the risk of MINS was starting to increase more compared to the thresholds of 70 and 75 mmHg, but 20% was not a change point from (C) and (D).