Blood loss and survival. (A) Blood loss measured at 12 min (before intervention) and 300 min after injury. Data are shown as scatter plots (n = 8 for each study group), with horizontal lines representing mean and vertical lines representing interquartile range. (B) Survival data are presented as a Kaplan–Meier curve. PCC = prothrombin complex concentrate. *P < 0.05 versus PCC50 and PCC100.