Fig. 9. Dexmedetomidine (DMT) suppresses long-term potentiation in the presence of prazosin (PRZ). (  A ) Sample traces recorded in the presence of prazosin (1 μm) just before θ-burst stimulation (TBS) (a), immediately after TBS (b), or 60 min after TBS (c). (  B ) Sample traces recorded at the same time points in the presence of prazosin (1 μm) and DMT (50 nm). (  C ) DMT attenuated long-term potentiation in the presence of prazosin (n = 8 , P < 0.05 , filled circles ) compared with vehicle (n = 8 , open circles ). fEPSP = field excitatory postsynaptic potential.