Fig. 4.
Endothelial function indicators in swine. (A) Cell-free hemoglobin in washed (wash) and rejuvenated (Rej.) porcine red blood cells units. (B) Cell-free hemoglobin levels in porcine plasma samples. (C) Interleukin-8 levels in porcine samples. (D) Heme oxygenase 1 expression in porcine kidney tissue obtained from at least three animals per group. (E) Serum creatinine levels. (F) Pulmonary vascular resistance index. The values represent means ± SD, and the P value in (C) indicates significant differences between the groups (Supplemental Digital Content, https://links.lww.com/ALN/B555 and https://links.lww.com/ALN/B556, for details). Post = postintervention measure; Pre = preintervention measure.