Figure 5. Effects of isoflurane on superoxide production determined by the reduction of ferricytochrome c. The ferricytochrome c reduction is expressed as the difference in absorbance between perfused and nonperfused solutions. Values are mean +/- SD. *In the absence of superoxide dismutase, the control group with hypoxia was significantly different from the control group with hypoxia (P = 0.0038), the isoflurane group with hypoxia (P = 0.0017), and the isoflurane group with hypoxia (P = 0.0043 by one-way analysis of variance followed by Scheffe's F test).