Fig. 4. Radial arm maze acquisition performance of adult mice treated with vehicle (0.9% NaCl), 5 mg/kg thiopental (Thio L), 25 mg/kg thiopental (Thio H), 10 mg/kg propofol (Prop L), 60 mg/kg propofol (Prop H), 25 mg/kg ketamine (Ket), 25 mg/kg ketamine plus 5 mg/kg thiopental (Thio L + Ket), or 25 mg/kg ketamine plus 10 mg/kg propofol (Prop L + Ket) on neonatal day 10 and tested in the radial arm maze at 63 days of age. Number of errors and total time (seconds) on 3 consecutive days of testing. A = significant difference versus vehicle; B = significant difference versus all monotherapy groups; C = significant difference versus all monotherapy groups except ketamine. Letters in uppercase and lowercase represent 1% and 5% levels of significance, respectively.