Fig. 5. Activation of leukocytes. CD11b expression was used to demonstrate granulocyte ( A ) and monocyte ( B ) activation after ischemia–reperfusion in the ischemic limb. Note the shift in fluorescence intensity to lower values in the time-matched sevoflurane sample ( C ). Data are mean ± SD. CTL = control protocol; MFI = mean fluorescence intensity; SEVO = sevoflurane protocol.