Fig. 1. (  A ) Effect of protein kinase C (PKC) inhibition (3 μm bisindolylmaleimide I) on acetylcholine contraction in endothelium-denuded pulmonary veins. (  B ) Effect of conventional PKC (cPKC) isozyme inhibition (1 μm Gö7936) on acetylcholine contraction in endothelium-denuded pulmonary veins. Inhibition of PKC (  P < 0.001) and cPKC (  P = 0.002) attenuated acetylcholine contraction. n = 6.