Fig. 6. Relation of the observed hydroxyethyl starch (HES) plasma concentration values to the observed effects as during acute normovolemic hemodilution with HES 650/0.42 (n = 12) and HES 130/0.42 (n = 12), respectively (  A –  C ). Relation of the measured HES molecular weight to the observed effects during acute normovolemic hemodilution with HES 650/0.42 (n = 12) and HES 130/0.42 (n = 12), respectively (  D –  F ). *  P < 0.05 for the slope of HES 650/0.42  versus HES 130/0.42. ns = not significant (  P > 0.05) for the slope of HES 650/0.42  versus HES 130/0.42. aPTT = activated partial thromboplastin time; CI = coagulation index; Hb = hemoglobin concentration.