Fig. 6. Influence of acute late sepsis or rocuronium on critical depolarization of muscle membrane. Critical depolarizations in the cecal ligation and puncture (CLP) group ( filled columns ) were significantly ( P < 0.05 or P < 0.01) smaller than those in the sham group ( open columns ) at 0 (baseline), 5, and 15 μm rocuronium, but there was no significant difference between critical depolarization at 0 μm rocuronium (baseline) and that at 5 or 15 μm rocuronium in both the sham and CLP groups. * P < 0.01 versus sham; ** P < 0.05 versus sham; n = 25 at 0 (baseline), 5 and 15 μm rocuronium, each.