Fig. 1. Photograph and cartoons of a macroemulsion and microemulsion of propofol. ( A ) Shown in the photograph is an opaque, white macroemulsion (Macro) and a clear, colorless microemulsion (Micro) of propofol. ( B and C ) Cartoon demonstrating the relative particle sizes of the macroemulsion ( B ) and microemulsion ( C ). ( D ) Cartoon of a microemulsion in cross section. ( E ) Magnified view of cross section of a microemulsion particle demonstrating propofol surrounded by a corona of purified poloxamer 188 and sodium caprylate surfactant in a bulk media of normal saline. Calibration bars apply only to their respective panels. Color legend applies to all panels.