Fig. 2. Flow cytometry of sorted cultured mouse neurons stained with propidium iodide (for cell death) and annexin V (for apoptosis). ( A ) Untreated controls. Brief exposure of cortical neuronal cells in primary culture to glutamate (300 μm) resulted in a significant decrease in cell viability ( B ). Exposure to xenon doubled the number of viable cells ( C ), and this improvement was exclusively due to a reduction in the amount of apoptosis ( D ). ** P < 0.01 versus control. Reproduced with permission. 67