Fig. 1. The patient sample was analyzed by automated sequencing for mutation G7300A in exon 45 of the ryanodine receptor gene, leading to a substitution of glycine for arginine at position 2434. The base pair ambiguity is shown in A in the middle of the sequence (-), where two peaks, one for adenine and one for guanine, represent the mutated and wild-type allele. A wild-type control sample is represented in B .