Fig. 2. Neuronal density (viable neurons/mm²) in hippocampal CA1 region (  A ) and parietal neocortex (  B ) of naive or sham-operated rats compared with neuronal density 7 days after 15 min of global cerebral ischemia with vehicle (n = 25, pooled) or erythromycin pretreatment (25 mg/kg intramuscularly) 6 h (n = 12), 12 h (n = 8), or 24 h (n = 7) before the injury. Erythromycin pretreatment increased the density of viable neurons after ischemia. *  P < 0.05  versus sham operation; **  P < 0.05  versus vehicle pretreatment, analysis of variance and  post hoc Student-Newman-Keuls test. E = erythromycin pretreatment.