Fig. 6. Expression of heme oxygenase 1 (HO-1) and heme oxygenase (HO) activity in the liver after pentobarbital (PENTO) or isoflurane (ISO) anesthesia, with or without chelerythrine (ISO + Chel) or quinacrine (ISO + Quin). The two lanes corresponding to each intervention show the results of two representative experiments. ( C ) Densitometric analysis of HO-1 messenger RNA (mRNA) and ( D ) HO activity of all individual experiments (n = 5–7/group). * P < 0.05 versus pentobarbital. # P < 0.05 versus isoflurane.