Fig. 3. Mean (± SEM) lung lavage neutrophils numbers (cells × 104/ml) ( A ) and alveolar neutrophil numbers (cells per high-power field) in lung tissue sections ( B ) at the termination of low- or high-tidal-volume mechanical ventilation in controls or animals treated with fucoidin or granulocyte colony-stimulating factor (G-CSF). Compared with controls, fucoidin significantly reduced lung lavage neutrophils with high tidal volumes, and G-CSF significantly increased both lung lavage and histology neutrophils with low tidal volumes.