Fig. 1. Schematic drawings of a 1-cm-long incision and suturing for behavioral experiments in which mechanical stimuli were applied to a primary area (an area adjacent to) ( A ) and a secondary area (an area distant from) ( B ) the incisional injury. Threshold of withdrawal in response to von Frey hair stimulation ( C, D ) and the scores of responses to brush stimulation ( E, F ) in the primary area and the secondary area after the incision. # P < 0.01 versus preincision values; * P < 0.05 versus preincision values.