Fig. 5. F6 has no effect on IPSC frequency. ( A ) Cumulative probability and amplitude histograms (insets) of mIPSCs. There was no systematic change with F6 40 μm. ( B ) Cumulative probability and amplitude histograms (insets) of sIPSCs. As for mIPSCs, there was no change in the cumulative probabilities and amplitude distributions in the presence of 25 μm F6. ( C ) The ratio of the IEI in F6 divided by the IEI under control conditions (IEIF6/IEIcontrol) is plotted against the concentration of F6 for all mIPSC experiments. IEI =interevent interval; IPSC =inhibitory postsynaptic current; mIPSC =miniature inhibitory postsynaptic current; sIPSC =spontaneous inhibitory postsynaptic current.