Fig. 2. Myocardial infarct size expressed as a percentage of the left ventricular area at risk. CEL = celecoxib; CON = control; ISO = isoflurane; M = administration of celecoxib during mediator phase (2.5 h before left anterior descending coronary artery occlusion); T = administration of a single dose celecoxib during the trigger phase (30 min before exposure to isoflurane). * Significantly (P < 0.05) different from control.