Fig. 4. Isoflurane induced an increase in excitatory amino acid transporter type 3 activity. C6 cells were exposed to 2% isoflurane for 7 h at 37°C and then incubated with 10 μm L-[³H] glutamate in the absence of isoflurane for 5 min at 37°C. Data are mean ± SD after subtraction of background (Na⁺-independent uptake, n = 18). *P < 0.05 compared with control. #P < 0.05 compared with dihydrokainate alone. C = control; Iso = 2% isoflurane; DHK = 300 μm dihydrokainate.