Fig. 4. Effects of heme oxygenase-1 (HO-1) induction, zinc protoporphyrin IX (ZnPP), bilirubin, carbon monoxide (CO), and anti-glycoprotein Ibα monoclonal antibody GUR83/35 on lipopolysaccharide-induced leukocyte rolling, evaluated as V^W/V^Rvalues, in the mesenteric venules. HO-1 was induced with hemin 12 h before the experiments. The data are expressed as mean ± SD of four to eight experiments in each group. *P < 0.05 as compared with the hemin-untreated control; †P < 0.05 as compared with the hemin-untreated lipopolysaccharide.