Fig. 7. Norepinephrine (50 μm) did not affect a sensitivity of substantia gelatinosa neurons to AMPA. (A ) Chart recording of miniature excitatory postsynaptic currents (mEPSCs) in the absence and presence of norepinephrine. (B ) mEPSCs, shown in an expanded time scale, in the absence (left ) and presence (right ) of norepinephrine for a period indicated by a mark shown below the chart recording in A . (C ) Cumulative distributions of the amplitude (left ) and interevent interval (right ) of mEPSCs before (continuous line) and during (dotted line) 1 min after the application of norepinephrine (NE), which were obtained by analyzing 645 and 702 mEPSC events, respectively. Norepinephrine had no effect on their distributions (P > 0.05; Kolmogorov-Smirnov test). (D ) AMPA (10 μm) responses, obtained by its superfusion for 30 s, in the absence and presence of norepinephrine. VH=−70 mV.