![Fig. 3. Concentration-effect curve for the DAMGO-stimulated [35S]GTPγS binding in the spinal cord membrane obtained from normal and diabetic rats 4 weeks after streptozotocin injection. The data are expressed as the percentage of basal [35S]GTPγS binding (mean ± SEM, n = 4 in each group). *P < 0.05 compared with the value in the normal group at the same concentration of DAMGO. The basal [35S]GTPγS binding was significantly higher in diabetic rats than normal rats (56.3 ± 3.0 vs. 49.5 ± 2.3 fmol/mg protein).](https://asa2.silverchair-cdn.com/asa2/content_public/journal/anesthesiology/97/6/10.1097_00000542-200212000-00037/2/37ff3.png?Expires=1716539725&Signature=a2pNr4Ydffcb7~WVwqiNYgboPEv6qmsLapUD~5940j4paq8XS~HjBhw05nvkv5U5Udj6irDL60lKmfkbFoPfUfpnWnROuHZWtdFN-c8hn4aJfr1p5lDWiVK8sKX2MKVBVyIHw1-IEdZNR1G~OHiXbrkCqnQDzNCUInR1H5bvrAQ-hypy2bKXW222P7XtRSymazqEaT59xn9ynpk1zNruFmLZDOquqXwuiBO7bOT48dVEQcqW0W1NX7RyBdxpXOYSO8zd5ugwnMQVgIVGEAvDmxMMcR~UUGBJp~iyB7sa08WOPVz3vKpy8lm6~6sWuNP3RAsk8BaiNvk0Ag5SkxJo4w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Fig. 3. Concentration-effect curve for the DAMGO-stimulated [35S]GTPγS binding in the spinal cord membrane obtained from normal and diabetic rats 4 weeks after streptozotocin injection. The data are expressed as the percentage of basal [35S]GTPγS binding (mean ± SEM, n = 4 in each group). *P < 0.05 compared with the value in the normal group at the same concentration of DAMGO. The basal [35S]GTPγS binding was significantly higher in diabetic rats than normal rats (56.3 ± 3.0 vs. 49.5 ± 2.3 fmol/mg protein).
