Fig. 2. Line plot showing the time course of heart rate, cardiac output, and left ventricular peak systolic pressure (LVSP) during experiments in the control, isoflurane, isoflurane + MPG, MPG, isoflurane + MnTBAP, and MnTBAP groups. Data are mean ± SD. MPG =N -(2-mercaptoproprionyl) glycine application; MnTBAP = Mn(III)tetrakis(4-benzoic acid)porphy-rine chloride application. †P < 0.05 versus baseline conditions; *P < 0.05 compared with the isoflurane group.