Fig. 2. Results of quantitative densitometry of [35S]GTPγS binding shown as mean values of percent change from normal spinal cord baseline ± SEM. (Top ) Ipsilateral baseline [35S]GTPγS binding in normal (0.68 ± 0.07 nCi/g) and spinal nerve–ligated (SNL; 1.01 ± 0.11 nCi/g) dorsal horns and binding after stimulation with 1 um R-N6-phenylisopropyladenosine (R-PIA) of normal and SNL animals. (Bottom ) Contralateral baseline [35S]GTPγS binding in normal (0.63 ± 0.08 nCi/g) and SNL (0.91 ± 0.07 nCi/g) dorsal horns and binding after stimulation with 1 um R-PIA of normal and SNL animals. #P < 0.05 compared with normal baseline; *P < 0.05 compared with SNL baseline; §P < 0.05 between R-PIA–stimulated normal and SNL animals.

Fig. 2. Results of quantitative densitometry of [35S]GTPγS binding shown as mean values of percent change from normal spinal cord baseline ± SEM. (Top ) Ipsilateral baseline [35S]GTPγS binding in normal (0.68 ± 0.07 nCi/g) and spinal nerve–ligated (SNL; 1.01 ± 0.11 nCi/g) dorsal horns and binding after stimulation with 1 um R-N6-phenylisopropyladenosine (R-PIA) of normal and SNL animals. (Bottom ) Contralateral baseline [35S]GTPγS binding in normal (0.63 ± 0.08 nCi/g) and SNL (0.91 ± 0.07 nCi/g) dorsal horns and binding after stimulation with 1 um R-PIA of normal and SNL animals. #P < 0.05 compared with normal baseline; *P < 0.05 compared with SNL baseline; §P < 0.05 between R-PIA–stimulated normal and SNL animals.

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