Fig. 1. Lack of effect of racemic thiopental on excitatory glutamatergic currents. (A ) Representative traces showing the lack of effect of 50 μm thiopental on glutamatergic synaptic currents. (B ) The amplitude of the excitatory postsynaptic current (EPSC) does not change significantly over the clinically relevant range of concentrations. (C ) The total charge transfer (the total area under the EPSC), which also does not change significantly, is plotted as a percentage change from the control value on the same scale as that used in fig. 3C. The points represent mean values (for an average of 19 cells). In both cases the lines are drawn by eye and have no theoretical significance.