American Society of Anesthesiologists

Fig. 1. Alveolar fluid clearance (% instilled) over 1 h, after intraalveolar lidocaine (10−5m; n = 5) or intravenous lidocaine (2 mg/kg + 2 mg · kg−1· h−1; n = 6) with the same range of plasma concentration. Alveolar fluid clearance was decreased in both groups after lidocaine compared with control rats (n = 6). Values are mean ± SE. *P < 0.05 versus controls.

Fig. 1. Alveolar fluid clearance (% instilled) over 1 h, after intraalveolar lidocaine (10⁻⁵m; n = 5) or intravenous lidocaine (2 mg/kg + 2 mg · kg⁻¹· h⁻¹; n = 6) with the same range of plasma concentration. Alveolar fluid clearance was decreased in both groups after lidocaine compared with control rats (n = 6). Values are mean ± SE. *P < 0.05 versus controls.

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