Fig. 2. (A ) Courses of mean blood pressure (BP) and heart rate (HR) were similar after administration of all drugs with transient increases in BP and HR within 1 min after injection. (B ) Venous ketamine and (nor)-ketamine plasma concentrations mirrored the drug dose ratio applied. (C ) Changes in venous epinephrine and norepinephrine plasma concentrations were comparable after all drugs. Symbols denote the mean ± SD.