Fig. 2. Original tracing demonstrating effects of propofol on pulmonary arterial strips without endothelium after phenylephrine (PE; 10−5m) precontraction in the absence (left ) and presence (right ) of ibuprofen (10−5m). Propofol (10−4m) potentiated phenylephrine-induced increases in intracellular Ca2+concentration (340/380 ratio) and tension. Pretreatment with ibuprofen abolished the propofol-induced potentiation (bottom , n = 6 each). * P < 0.05 compared with strips without ibuprofen treatment. W = washout of strips with fresh medium.