Fig. 5. Analysis of isometric Ca2+back-titration experiment (part 2 of 3). Effects of myoplasmic Ca2+availability (described here as SR release) and of myofibrillar Ca2+sensitivity (described here as the variable B of equation 4in appendix) on the sums of squared differences between observed and simulated aequorin luminescence (top ) and absolute difference between observed and simulated Ca2+occupancies of TnC (bottom ) for the Ca2+back-titration experiment of figure 4. The solid line on each mesh plot runs through the minimal values of the surface.