American Society of Anesthesiologists

Fig. 5. Concentration–effect curves summarizing the effects of etomidate (10−4m) and ketamine (10−4m) on the l-NAME–resistant (A and B ) and TBA-resistant (C and D ) components of bradykinin-induced relaxation in ibuprofen (IBU)-pretreated rings. Pulmonary arterial rings were precontracted to the ED50level of tension with phenylephrine. Etomidate and ketamine attenuated (* P < 0.05) the l-NAME–resistant and TBA-resistant relaxation.

Fig. 5. Concentration–effect curves summarizing the effects of etomidate (10⁻⁴m) and ketamine (10⁻⁴m) on the l-NAME–resistant (A and B ) and TBA-resistant (C and D ) components of bradykinin-induced relaxation in ibuprofen (IBU)-pretreated rings. Pulmonary arterial rings were precontracted to the ED⁵⁰level of tension with phenylephrine. Etomidate and ketamine attenuated (* P < 0.05) the l-NAME–resistant and TBA-resistant relaxation.

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