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Table 4. Pharmacokinetic Model Parameter Estimates (Mean ± SE)

See Results for description of pharmacokinetic parameters.

Formula used: V2= k12/k21· V1; Cl1= V1· k10; Cl2= V1· k12

* The weight adjusted terms containing kg−1as a unit need to be multiplied by the patient's weight in kg to calculate the parameter. For example an 80-kg patient, pre-CPB could have a V1(l) = 80 kg · 0.149 l · kg−1− 1.61 l = 10.3 l.

SE = standard error; CPB = cardiopulmonary bypass.

Table 4. Pharmacokinetic Model Parameter Estimates (Mean ± SE)
Table 4. Pharmacokinetic Model Parameter Estimates (Mean ± SE)
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