Table 4. Pharmacokinetic Model Parameter Estimates (Mean ± SE)

See Results for description of pharmacokinetic parameters.

Formula used: V²= k¹²/k²¹· V¹; Cl¹= V¹· k¹⁰; Cl²= V¹· k¹²

* The weight adjusted terms containing kg⁻¹as a unit need to be multiplied by the patient's weight in kg to calculate the parameter. For example an 80-kg patient, pre-CPB could have a V¹(l) = 80 kg · 0.149 l · kg⁻¹− 1.61 l = 10.3 l.

SE = standard error; CPB = cardiopulmonary bypass.