Table 8. Effect of Resuscitation with Hydroxyethyl Starch (HES) and Isotonic Saline (NaCl) on Laboratory Parameters 24h after Induction of Endotoxemia

Data are mean ± SD. HES represents animals (n = 7) that received LPS (2 mg/kg body wt) and HES (16 ml/kg body wt/h) 3h after the induction of endotoxemia, whereas NaCl represents animals (n = 6) that received LPS (2 mg/kg body wt) and isotonic saline (66 ml/kg body wt/h) 3h after induction of endotoxemia. Control represents animals (n = 8) which received LPS (2 mg/kg body wt) only. Normal standard values were derived from eight healthy animals without any treatment.

*= significant differences (P < 0.05) of HES versus  NaCl (ANOVA, Student Newman–Keuls test),

†= significant differences (P < 0.05) of normal values versus  NaCl, HES and controls (Kruskal–Wallis ANOVA, Mann–Whitney U test).