Table 6. Macrohemodynamic Effects of Resuscitation with Hydroxyethyl Starch (HES) and Crystalloid Volume Support (NaCl) during Endotoxemia

Data are mean ± SD. HES represents animals (n = 5) that received LPS (2 mg/kg body wt) and HES (16 ml/kg body wt/h) 3h after the induction of endotoxemia, whereas mNaCl represents animals (n = 5) that received LPS (2 mg/kg body wt) and isotonic saline (66 ml/kg body wt/h) 3h after induction of endotoxemia. Control animals (n = 4) received LPS (2 mg/kg body wt) without volume. Mean arterial pressure (MAP) and heart rate (HR) were measured via carotid artery catheters. There were no significant differences between the groups at the respective time points. Also, intragroup comparisons to baseline did not show significant changes.