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Table 1. Time to Trigger Malignant Hyperthermia, Malignant Hyperthermia Diagnosis, Masseter Bulb Pressures, and Epinephrine Administration in Malignant Hyperthermia–Susceptible Animals Exposed to Succinylcholine 2 mg/kg In Vivo 

* Died at 5 min.

† 30 min after first dose of succinylcholine, second dose of succinylcholine and halothane 2 minimum aveolar concentration; 10 minutes until PaCO2>70 mmHg.

‡ 90 min after first dose of succinylcholine, second dose of succinylcholine; 15 minutes until PaCO2> 70 mmHg.

§ 70 min after first dose of succinylcholine, 10 min after second dose of vecuronium; exposure to halothane 1 minimum aveolar concentration (0.87%); 30 minutes until PaCO2> 70 mmHg.

MH = malignant hyperthermia; MHS = malignant hyperthermia–susceptible (no pretreatment); MHS D = pretreatment with dantrolene 2.5 mg/kg intravenous; MHS V = pretreatment with vecuronium 1 mg/kg intravenous; IVCT =in vitro  contracture test.

Table 1. Time to Trigger Malignant Hyperthermia, Malignant Hyperthermia Diagnosis, Masseter Bulb Pressures, and Epinephrine Administration in Malignant Hyperthermia–Susceptible Animals Exposed to Succinylcholine 2 mg/kg In Vivo 
Table 1. Time to Trigger Malignant Hyperthermia, Malignant Hyperthermia Diagnosis, Masseter Bulb Pressures, and Epinephrine Administration in Malignant Hyperthermia–Susceptible Animals Exposed to Succinylcholine 2 mg/kg In Vivo 
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