Table 3. Multivariate Predictors of Postoperative Peak Serum Creatinine Concentration in 564 Patients after Coronary Bypass Surgery
The apolipoprotein E genotype group explains approximately as much variability in postcoronary bypass surgery as can be explained by the combined influences of two known renal dysfunction risk factors, diabetes and hypertension. Genotype assignment to the most common (i.e. , E3 = 3/3) or to the less common genotype groups (i.e. , E2 = 2/2, 2/3, 2/4; E4 = 3/4, 4/4) is determined by the presence of ϵ2 and ϵ4 alleles.