Table 3. Pharmacokinetic–Pharmacodynamic Fitting Results for the Unbound Receptor Model
EC50is a calculated value and not a model parameter; molecular-weight rocuronium = 609.69. Values are shown as median with range in parentheses.
β= exponential coefficient of twitch height–unbound receptor concentration relation; EC50= rocuronium concentration at 50% effect; ke0= rate constant between plasma and effect compartment; Rtot= total receptor concentration; URM = unbound receptor model.