Table 1. Caffeine Halothane Contracture Test Data and Clinical Profile of Susceptible Individuals with Malignant Hyperthermia in the Study

Values indicate mean tension (g) of three strips. Diagnosis of malignant hyperthermia was made using three muscle strips for halothane and three for caffeine contracture.

*This patient is III-3 shown in figure 3A.

CHCT = caffeine halothane contracture test; CE = patient had either suspected or confirmed clinical episode; FH = patient had a family history of either suspected or confirmed clinical episode; Not detected = not detected after screening 21 known mutations.