Table 2. Effect of Coinjecting the Amitriptyline, Bupivacaine, and Epinephrine Admixture at Various Concentrations on the Cutaneous Analgesia Elicited

All values are expressed as mean ± SE, except for fractions.

*P < 0.05, t  test comparison with the value of the corresponding duration of complete block of the equivalent total amount of bupivacaine (i.e. , either 0.25 or 0.5%, respectively) injected separately with epinephrine.

†P < 0.05, t  test comparison when the value for the coinjected combination was significantly more than the corresponding value for the equivalent total amount of individual drug (i.e. , 0.25 and 0.5%, respectively) of both amitriptyline alone with epinephrine and bupivacaine alone with epinephrine.