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Table 2. Effect of Nitric Oxide Synthase Inhibition (l-NAME) on Isoflurane-induced Hyperpolarization of Vascular Smooth Muscle (VSM)

Values are mean mV ± SD. For sequential measurements of in situ  VSM transmembrane potential, physiologic salt solution superfusate contained the following: (1) no agent (denervated control), (2) 0.6 mm isoflurane (ISO), (3) either 50 μm or 1 mm l-NAME (after washout of isoflurane), (4) l-NAME + isoflurane.

* Different from control,

† different from both control and isoflurane,

§ different from isoflurane,

‡ different from l-NAME;P ≤ 0.05; n = 8.

WKY = Wistar Kyoto; SHR = spontaneously hypertensive rat.

Table 2. Effect of Nitric Oxide Synthase Inhibition (l-NAME) on Isoflurane-induced Hyperpolarization of Vascular Smooth Muscle (VSM)
Table 2. Effect of Nitric Oxide Synthase Inhibition (l-NAME) on Isoflurane-induced Hyperpolarization of Vascular Smooth Muscle (VSM)
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