Table 2. Effect of Nitric Oxide Synthase Inhibition (l-NAME) on Isoflurane-induced Hyperpolarization of Vascular Smooth Muscle (VSM)
Values are mean mV ± SD. For sequential measurements of in situ VSM transmembrane potential, physiologic salt solution superfusate contained the following: (1) no agent (denervated control), (2) 0.6 mm isoflurane (ISO), (3) either 50 μm or 1 mm l-NAME (after washout of isoflurane), (4) l-NAME + isoflurane.
* Different from control,
† different from both control and isoflurane,
§ different from isoflurane,
‡ different from l-NAME;P ≤ 0.05; n = 8.
WKY = Wistar Kyoto; SHR = spontaneously hypertensive rat.