Table 1. Kinetic Parameters for the Recovery of Na+Current after Prolonged Depolarization*
* Cells were conditioned with a 10-s depolarizing pulse to +10 mV from a holding potential of −100 mV and the recovery at −10 mV after the long depolarization was determined by giving a test pulse to +10 mV at various times after the conditioning pulse. The data were normalized to the amplitude of the test pulse obtained after a 50-s recovery time and fitted by the sum of two exponentials.
† Fraction of current recovering with the slower time constant.
‡ Both enantiomers at 0.3 mm; n = 4 for all values.