Table 2. Results of the Regression Procedure
(1) two-compartment model; (2) three-compartment model; (3) Cl1=θ1· (BW/70); (4) Cl1=θ1· (BW/70)θ7; (5) Cl2=θ3· (BW/70)θ8; (6) V2=θ4· (BW/70)θ9; (7) Cl1=θ1· (BW/70)θ7− (age − 60) ·θ10; (8) Cl3=θ5· (BW/70)θ11; (9) V1=θ2· (BW/70); (10) V1=θ2· (BW/70)θ12· (age/30)θ13; (11) Cl2changed for venous samples as noted in table 3; (12) Cl2, Cl3, V1, and V2changed for bolus data as noted in table 3; MWR = median weighted residual; MAWR = median absolute weighted residual.
*−2LL is the value of the objective function (−2 log likelihood).
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