Table 4. Pharmacokinetic Parameters of the Model Determined for 3-Desacetylvecuronium and the Influence of Core Temperature on Each Parameter^*

* Where justified; all parameters are normalized to f  ^metabolized(i.e.,  they are presented as if all vecuronium were converted to 3-desacetylvecuronium; if only half is converted the parameters will be half this magnitude). Where gender values differ, the primary value in the tableis for women.

† The 95% confidence interval for this effect calculated using the standard error includes the value 0, but the true 95% confidence interval is likely to be asymmetrical; therefore, we included it in the model because the parameter is statistically justified.