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Table 1. Regional CBF Changes after FPI in Newborn Pigs Untreated and Pretreated with ZD 7155 and PD 123,319 during Normotension and Moderate and Severe Hypotension

Pretreated animals received 1 mg/kg ZD 7155 or 0.5 mg/kg PD 123,319. n = 6.

*P < 0.05 compared with corresponding preinjury value (control).

P < 0.05 compared with corresponding normotension value.

P < 0.05 compared with corresponding non-ZD 7155 pretreated value.

CBF = cerebral blood flow; FPI = fluid percussion injury; MOD = moderate hypotension; NOR = normotension; SEV = severe hypotension; vehicle = untreated animals.

Table 1. Regional CBF Changes after FPI in Newborn Pigs Untreated and Pretreated with ZD 7155 and PD 123,319 during Normotension and Moderate and Severe Hypotension
Table 1. Regional CBF Changes after FPI in Newborn Pigs Untreated and Pretreated with ZD 7155 and PD 123,319 during Normotension and Moderate and Severe Hypotension
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